SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea1436f3fc4ae0b97ade31b1dd6639060253b551635feba47382b19179f8aea' 
  AND token = 'CUEj0TycFxDbhmiTVUJE9IoE1tImToVIQktOgAst2Ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}