SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fac964c27454050ea350781a4109a076d10b45e1ddb64fa2df0026a462682875' 
  AND token = 'sVQtiue2SCtiCGQ5b3DabqUgROk/IkBBQsRIfGJ4xh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}