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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9c2f598bee6ed4dbc2d4a5bd5ea027498d73b081482fffe257857bce5f29487' 
  AND token = 'Uh1jN0wDqLlQsNF0DDEU1zJdB9A9U0iU8+upSxbR0dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}