SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed695d367b06879e81e4ca77095a37fd0647a43250e705a8084adb16e11a9e9' 
  AND token = '2JNHDbaKl9zFR9+9yBX/XA1ANorkOs6xRAxioBq6Lt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}