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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53ff95e8659f7a1eefe0d3fdeef19b86fc57a429a2c9054cfaf066406ad0550a' 
  AND token = 'AB8q4RawtlmUiuTFSnlj+oskwS1tXNtfeW4T0w5dPhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}