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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f11295c513d021132aff45bd2b357548c52cd7f7e4fde6ad5b2020c3c8152d5' 
  AND token = 'RYgLd9s2j8wHO35XMNyWTFr57fS9N4ed6SrVO/glPKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}