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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dda02f3aed8079985cf3b2cefaf69c460a8dbb4c42cbcbf223a2c599c413307' 
  AND token = 'jIC1aeLkY2RPQN5gBaw4tNpwepmsPt8/IFNtuKDYeL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}