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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4774aff27982f6ae534cf6caa365707a4017ccff8301cf344c224321d0166dc7' 
  AND token = '+0niq3SdyVKF0cMgMROA11YZqmUZ3qDF2gM2cd0ytsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}