SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e87becd1a9dd6cd79f106c769a1b0eb7b56c7e624e7840e99bc685fbc35f0d1' 
  AND token = 'rF1J7P3E6Wq2s9E+6hwfsa2fvXOMI/yRkDS9qHKOlpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}