SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c49895fa338fb76b78b1b890fa371e8fc93ba6b9d9a9247c77d6b4df57a93d' 
  AND token = 'u9iXqgf7d/h+UYJHkffn1QTNWSvdccS83G8ambfW57k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}