SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a37a329fe09738b8aea24a416a6df8720a786444b36b0340fe79c458b464c8d' 
  AND token = 'UTdYWbcJTZKoowfQpQJMnlzso+vwAMgQklPz2Xl14M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}