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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dc20545e3aded1ed542ce457181ad266036d7f23c23e7013cc0e49f2b5bc3f5' 
  AND token = 'qLWi2/wS/RBcQTHIzzIzakEGuol6aWoAPi3CHtD3UlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}