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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a5d9445f2ae79d57de42e485aeaa17a4df6058079b1b4b52dba9583bb0f1d1e' 
  AND token = 'Rz6CCymSRpkt3C8Cv1AINazCsJQVlsHIvcxjIvmUQL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}