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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f3b78d85f4eb8fdab7ad01a94c0905b020be53c3b083433e15fbee61e114cc3' 
  AND token = 'gE2H2MjWONNC7Jo3BXOPDUbWq2NkT8QxRezDpZZCKc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}