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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '488bf39d13ef566412faedcf02f922c49e1e566e3fc8ee1518d71dbe9e0d3b22' 
  AND token = 'IMBLk3Azkw2FdvvJ8XK/IYIWO6OW7V2UHoye1Aa9sCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}