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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd020e7252c6e6cb5d1840b3c3a82ffdb45020268519393d2e8726009c003b0b3' 
  AND token = 'apm37+1KMTSaW7gTgoymm/V9Ieh49+QZRGULSRtUjns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}