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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185f84b382cd20211af59fbce2c0745f5d669a2a68e24f463a8fcf0b981b84b9' 
  AND token = 'cL0uM0LBiJiz3B46eYQC0y/oGS3Q5Alf615TQSt6vOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}