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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0ec6eee3ab9c69426e4c32c222b9bbb93f22fcd618fe4f03b66ade91a3b663' 
  AND token = 'N6WRhFgluYjK9jKEtuaUwDr2ze3JPLhcBZUIl2NZVD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}