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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d0fa88a9451f7a7c4a9b03210203599976710443ed7192cb4a5839c994191e7' 
  AND token = 'xePFVTfSvY6NOn3ide91CNo2ptqeL8+aDv01yWktiUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}