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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4885295f22e7253dd5be305eaa2eefe1a437df95dc944cb28b770c22da1a5e99' 
  AND token = 'WvmbO2A8E0f73sATzQqgvdavVjH7LgRXsTCqga0aW6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}