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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a54684354fe84da5d8cd93b0dcb3d6ea9e2ea728ef99d9ea2bdad6c5140a307' 
  AND token = '8CBm2Yd4lcBaTaTitD0iN9ORI9d5iq7iPRnLysSqSeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}