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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f1b15bed36de63d84cde8a60fd4ecd672b03550bb3bcf2f6d7ad8e1079e7994' 
  AND token = 'clmelC9MB8HKVR+QH9CM76ax0akHF3flf/PBV9UXvc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}