SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6cc7bca520d01c680aadbb5608051cbaf3c2f3d95d2af406a880650178e6099' 
  AND token = 'NgVwqqRx5sdWjm5+GPCsMfmSijU5vGA49E+6+gqLLbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}