SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee67a724c237ca46743b51da34b371bd8dfb846a0cf66c299dc311bfed425f06' 
  AND token = 'ZZ2s5sEhDoaEZGGV1yQHgL+yu6QkPzNVmNcQ83CkNBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}