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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ddd65bbdc70e3aa08b098b538c61c8fb4741bbbb1ff891b5271127ae6e8da8c' 
  AND token = '3HQxIoKeZ/UbJLuM17E1bQkVkdY3jGOgMLv7W7mhKXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}