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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c61a5070a443b80c00ae9b09394cfed8be515fd3d76f7a5512d5461663be84a7' 
  AND token = 'CjCB7v4IUXLi0bxjTfJYuk/tmyFCXE+Z0a/I/KyW+1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}