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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed9727169a0462d1ded92ef6b6ded33305bc38749b5d2e78c8051a528c8b6b36' 
  AND token = 'Ef+z/WULt+wk++ZIr44cA6RD0vFTMzeTOJmSWjpIK00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}