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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48a9bb96d9e83f3c80264a1e92f5cd34359d9578362535eab688aa8654cab4bd' 
  AND token = 'eMe82SFYWd9loCxkTq32wBL2ZhpFZs5d1+NrjjCdeTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}