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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52da0bda2b6c68e179e83734f837ecfc775dfc2314531db6ef80f981955841c3' 
  AND token = 'eGhV9MwKbQg9KfPfd8+jV9uyiBRhSBOl8Adg0bubMvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}