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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15a9ad0994f13064a6ce4e7e0d3c5c57530c1a56440a212d99441d49ea15f9f6' 
  AND token = 'Avb6rw/pYF1n4Np2NVkbeHleXsAciiu9JnjIMVNRVxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}