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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6ddeb054edbee96aa0935f145fa40095def8b69bee4f56552039b6cd35adcc1' 
  AND token = 'dt/cW0h8aX8MT2arimxlHLR6NHiiwVh0tdmaPUMu78M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}