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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16215cdb01f02c677cc0dee0fa6d702a15180c74d06ab6439967eea638eb657e' 
  AND token = '++mXUuCDR4kxJUWh2HV7jCH3go3SE+VdIna7FLpMtVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}