SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60b4d37a10e229521c00bf94be4d308491be8a881bdb335fee4d8e487fec78e1' 
  AND token = 'Alrpxbgvq0BnrFFCjYZXdaP3OwRIoVe1EFGAfFd2cks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}