SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67a300e3cc3c583de3bf4095ef54e4f52c5855465c7ce8ed441701d23b4f231b' 
  AND token = '/sdrmKxuehi+tnLzG1GnSEaPI82dO+IfOl67jmAX2AE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}