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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa365f87fb71629047d437d5833ac4fc66c4e442273283cb49f7005eab1cafc' 
  AND token = 'fjbsdlMaVG9OZ9tiZWtmxF0yoJiBA1a3BGSeCY5lQj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}