SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fd64a267bdbcbb4d71c56d7bcc2ce7a84896a27bc988d517d965db5c397bd67' 
  AND token = 'ExdSZkxWA8VPByNgT9r011B5SMxmUGdCdifVBOR4bXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}