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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8899ea1b72aaab5acd98bcc647dc55bc8e0207891b0e51a55a0af236b1dc3ca6' 
  AND token = '1b+p+kxACCyGrKzUDG3G5zsXHT1rlyxxkJOja9ciZx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}