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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '485db7f50e751d60a01a3a21201e33d0ab5f12cd409eb6be78b791b2336ff990' 
  AND token = 'zIBs8et9a7XB+DKOsM9MTrxgG9iOX5LXN0jSFBI4UJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}