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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '041937cd6ade64fa2e1125e0c4be0614a8c80726add933886537b0e7d125a7d8' 
  AND token = 'zwUjc6KyldFMNn4NgSLFXRvfXbXpiVh8bFuiiOvbL0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}