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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '325420ef12d60955c5059ee450edfc1db3b9a10bdc89e6ae6518ef15feb4a36f' 
  AND token = 'XhX3I67uEKkiSTVlMz0/yHBr/6G6HQrCTritbJCy4mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}