SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ff4692e74a0076eedf30df11cd416122ba98c2c1ca23b144913c7c7be67dd4' 
  AND token = '/AswCF5ERx53cYiEa6QIulB93LpkLOxWx7w2ZkCtlEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}