SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5293b22e4ee2e8323a46325c46a8ee069cb139c1114ce935f461a848bdc26c48' 
  AND token = 'sFvOTaH+LQcc6g2WznpMgFtCaT53aklZwa/hS8egYWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}