SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff5e185dac2d6d65f2f8ec0dda5450459a2f8dbf977cfeb1452d25c99c167c48' 
  AND token = 'KhfwHiSLosfFwQ74iIPAPH4/gX9CJUEKNt4t6flm0NU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}