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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29434204252d4af5e5c9fa5c0b25003b34bb0feb32d20a2b235dce4b89529112' 
  AND token = 'VrfenrgRAZA9GcJX/tNfkSmlqna3XrnRnmgD4Smbhmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}