SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e430e23ae09590f0919b0134751c42c70d7eee428fd26f916570f5737513724' 
  AND token = 'ukWUtCg7zmSNLKzjkbvyE8oL5xYvdcp/gvcqJrQSrg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}