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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d424b09d64286b7e2d9082ba04903343ccfe2f05b8488926994b38f213053ce' 
  AND token = 'IwIyDg4dcwWXd+k8kxPUclq4ay5T1c0OydVtqxb6Tgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}