SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2343623cf08c43eff653c70d66ce925baec4297ad1c17fc2962f13be6b1535d8' 
  AND token = 'D25+IWYIeK1wI8YaYAKooQtokJc6PPqkJ5uMo4SmVdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}