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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72fd4165d38ab9da016af6cef7428dda42af7ae9a98706471ef348a0308c6c27' 
  AND token = '+qAA8zE/4DAlyZJ5yFg6oZ7GMXvHQJOj4x7i1WX1MI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}