SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8633c61fe6561b4be567e517db5530eb49f4f067f817559d2a6e6b85301320b' 
  AND token = 'WJatoeK8WJMzmMWFbY8PZcvvCfa+7aez9FO0BaEtL0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}