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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0866ec1396ba811dab04f5cead4975664cde725bab2a70ce2a45acb48c677a57' 
  AND token = '6Sfo2Vwyp/s+2CD6Qgio1glzg0R8pwn+Fvzp7Q4s18o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}